4 July, 2025
planned-c-sections-linked-to-higher-childhood-cancer-risk-study

In a striking revelation, researchers have found that babies born via planned caesarean section are significantly more likely to develop childhood cancer, particularly the most common form of childhood leukaemia. The study, conducted by scientists at the Karolinska Institute in Stockholm, examined data from nearly 2.5 million children born in Sweden between 1982 and 2015.

The research, published in the International Journal of Cancer, highlights that children born through planned C-sections have a 21% higher risk of developing acute lymphoblastic leukaemia (ALL) compared to those born naturally. This risk increases to 29% for B-cell acute lymphoblastic leukaemia (B-ALL), which represents about 80% of childhood ALL cases.

Analyzing the Data: A Closer Look

The comprehensive study reviewed birth records from two distinct periods, 1982 to 1989 and 1999 to 2015, to ensure robust findings. Of the children studied, 15.5% were delivered via caesarean section, categorized into planned and emergency procedures. Among these, 1,495 children eventually developed leukaemia, revealing a notable correlation between planned C-sections and increased cancer risk.

Interestingly, the research also found that the heightened risk was more pronounced in boys than girls and was particularly evident among younger children. This gender and age disparity in risk levels adds a complex layer to the findings, prompting further investigation into underlying causes.

Understanding the Implications

Experts suggest that the increased risk associated with planned C-sections could stem from the lack of exposure to natural birth stressors and beneficial bacteria in the birth canal. Dr. Christina-Evmorfia Kampitsi, the study’s lead author, emphasized the importance of these findings in the context of obstetric care.

“C-sections are an important and often life-saving part of obstetric care. We don’t want mothers to feel anxious about medically indicated C-sections. But when this result is combined with other study results showing that the risk of later asthma, allergies, or type 1 diabetes increases in children born by planned C-section, there is reason to discuss C-sections that are not medically indicated,” said Dr. Kampitsi.

The study also aligns with previous research linking planned C-sections to higher risks of asthma and food allergies, suggesting a broader impact on children’s health beyond cancer.

Historical Context and Future Considerations

The rise in C-section deliveries over recent decades has been a topic of extensive debate within the medical community. Historically, caesarean sections were reserved for emergency situations, but their use has expanded significantly, often due to convenience or scheduling preferences.

This development follows a broader trend of examining the long-term health impacts of birth methods. As more studies emerge, healthcare providers and expectant parents are urged to weigh the risks and benefits of planned C-sections carefully.

Meanwhile, the findings from the Karolinska Institute add a crucial dimension to ongoing discussions about optimizing childbirth practices to ensure the best possible outcomes for both mothers and their children.

Looking Ahead: The Path Forward

As the medical community continues to explore the implications of these findings, there is a growing call for more personalized approaches to childbirth. This includes considering the individual health needs and circumstances of each mother and child, rather than defaulting to planned C-sections without medical necessity.

Future research will likely delve deeper into the biological mechanisms linking planned C-sections with increased cancer risk, potentially guiding new clinical guidelines and public health strategies. For now, the study serves as a reminder of the complex interplay between birth methods and long-term health, underscoring the need for informed decision-making in obstetric care.