Science
New Study Links Ultra-Processed Diets to Male Fat Gain and Hormonal Changes

Recent research highlights the detrimental effects of ultra-processed foods on men’s health, revealing that such diets contribute to increased fat gain, hormonal disruptions, and exposure to harmful substances. This study indicates that not all calories are created equal, as men consuming a diet high in ultra-processed foods gained more fat compared to those eating unprocessed meals, despite similar caloric intake.
The research, led by Jessica Preston from the University of Copenhagen, found that men who followed an ultra-processed diet experienced significant changes in hormone levels, including a decrease in testosterone and an increase in harmful pollutants. The study’s findings challenge the common belief that overeating is the primary cause of weight gain, as the processing of food itself appears to be the main factor influencing health outcomes.
Study Overview and Methodology
A comprehensive analysis published in the British Medical Journal examined data from approximately 9.9 million people worldwide, linking ultra-processed foods to various health issues. These include an elevated risk of death from cardiovascular diseases, obesity, type 2 diabetes, sleep disturbances, and mental health concerns such as anxiety and depression.
To ensure accurate results, researchers recruited 43 men aged between 20 and 35 years. Each participant followed both an ultra-processed and an unprocessed diet for three weeks, separated by a three-month “washout” period. The study utilized a randomized approach, with half of the participants beginning with the ultra-processed diet, while the other half started with unprocessed foods. Participants consumed either a regular caloric intake or an additional 500 calories daily, but were unaware of which diet they were following.
Despite the calorie equivalence in both diets, results showed that men gained approximately 1 kilogram more fat while on the ultra-processed diet, indicating that the composition of the food significantly impacts body composition and health markers.
Understanding Ultra-Processed Foods
While there is no universal definition for ultra-processed foods, these products typically contain ingredients not commonly used in home cooking. This includes various chemicals, colorings, and sweeteners designed to enhance taste, appearance, or texture. The study revealed a worrying increase in the levels of hormone-disrupting phthalates, specifically cxMINP, in men consuming ultra-processed foods.
Additionally, participants on this diet exhibited reduced levels of both testosterone and follicle-stimulating hormone, which are critical for sperm production. The implications of these findings are significant, raising concerns about long-term reproductive and metabolic health.
Preston remarked, “Our results prove that ultra-processed foods harm our reproductive and metabolic health, even if they’re not eaten in excess. This indicates that it is the processed nature of these foods that makes them harmful.”
The authors of this study call for a reevaluation of nutritional guidelines to safeguard public health against chronic diseases linked to ultra-processed food consumption. The full research has been published in the journal Cell Metabolism, under the title “Effect of ultra-processed food consumption on male reproductive and metabolic health.”
This study sheds light on a critical public health issue, emphasizing the need for awareness regarding diet choices and their potential effects on overall health and well-being.
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